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Advantages of hyaluronic acid fat graft myringoplasty over fat graft myringoplasty.

TitleAdvantages of hyaluronic acid fat graft myringoplasty over fat graft myringoplasty.
Publication TypeJournal Article
Year of Publication2012
AuthorsSaliba I, Knapik M, Froehlich P, Abela A
JournalArch Otolaryngol Head Neck Surg
Date Published2012 Oct
KeywordsAdipose Tissue, Adolescent, Audiometry, Pure-Tone, Child, Child, Preschool, Female, Humans, Hyaluronic Acid, Male, Myringoplasty, Otoscopy, Prospective Studies, Speech Discrimination Tests, Tympanic Membrane Perforation

<p><b>OBJECTIVES: </b>To compare hyaluronic acid fat graft myringoplasty (HAFGM) with fat graft myringoplasty (FGM) on grade I tympanic membrane perforations (TMPs) (<25% of the tympanic membrane surface) and to assess 12-month postoperative hearing outcomes in a pediatric population.</p><p><b>DESIGN: </b>Prospective study.</p><p><b>SETTING: </b>Tertiary care pediatric center. PATIENTS Ninety-two children with a TMP were included in the study and were operated on using either the HAFGM (n = 50) or FGM (n = 42) technique. Age at surgery ranged from 4 to 17 years (mean age, 11.52 years).</p><p><b>INTERVENTIONS: </b>Hyaluronic acid fat graft myringoplasty is a new technique for TMP repair in a pediatric population and is performed using local anesthesia at the outpatient office.</p><p><b>MAIN OUTCOME MEASURES: </b>Postoperative status of the tympanic membrane, hearing improvement, and incidence of complications.</p><p><b>RESULTS: </b>Successful closure of the tympanic membrane was achieved in 90% of the HAFGM group and in 57.1% of the FGM group (P = .004). The mean (SD) postoperative air-bone gap in the HAFGM (6.86 [8.52] dB) group was significantly lower than in the FGM (18.32 [13.44] dB) group (P < .002). The mean postoperative follow-up time was 31.5 and 34.7 months for HAFGM and FGM groups, respectively. No difference was observed between children 10 years or younger and children older than 10 years. In the 2 groups, no postoperative complications were observed. The location of the perforation was not found to be a factor indicative of failure.</p><p><b>CONCLUSIONS: </b>The success rate of HAFGM is superior to that of FGM alone. Hyaluronic acid fat graft myringoplasty can be performed as an office-based procedure using local anesthesia and requires no hospitalization. Because of its substantial advantages, HAFGM could be considered as the first choice for the reconstruction of a dry TMP in the pediatric population.</p>

Alternate JournalArch. Otolaryngol. Head Neck Surg.
Citation KeyCK116
PubMed ID23069826