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Bedside differentiation of vestibular neuritis from central "vestibular pseudoneuritis".

TitleBedside differentiation of vestibular neuritis from central "vestibular pseudoneuritis".
Publication TypeJournal Article
Year of Publication2008
AuthorsCnyrim CD, Newman-Toker D, Karch C, Brandt T, Strupp M
JournalJ Neurol Neurosurg Psychiatry
Date Published2008 Apr
KeywordsAdult, Aged, Cerebral Infarction, Diagnosis, Differential, Electronystagmography, Female, Humans, Male, Meniere Disease, Middle Aged, Multiple Sclerosis, Neurologic Examination, Point-of-Care Systems, Retrospective Studies, Vertigo, Vestibular Function Tests, Vestibular Neuronitis

<p>Acute unilateral peripheral and central vestibular lesions can cause similar signs and symptoms, but they require different diagnostics and management. We therefore correlated clinical signs to differentiate vestibular neuritis (40 patients) from central "vestibular pseudoneuritis" (43 patients) in the acute situation with the final diagnosis assessed by neuroimaging. Skew deviation was the only specific but non-sensitive (40%) sign for pseudoneuritis. None of the other isolated signs (head thrust test, saccadic pursuit, gaze evoked nystagmus, subjective visual vertical) were reliable; however, multivariate logistic regression increased their sensitivity and specificity to 92%.</p>

Alternate JournalJ. Neurol. Neurosurg. Psychiatr.
Citation KeyCK70
PubMed ID18344397