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Detection of herpes simplex virus type 1 in human vestibular nuclei.

TitleDetection of herpes simplex virus type 1 in human vestibular nuclei.
Publication TypeJournal Article
Year of Publication2000
AuthorsArbusow V, Strupp M, Wasicky R, Horn AK, Schulz P, Brandt T
JournalNeurology
Volume55
Issue6
Pagination880-2
Date Published2000 Sep 26
ISSN0028-3878
KeywordsAdult, Aged, Female, Herpes Simplex, Herpesvirus 1, Human, Humans, Male, Middle Aged, Polymerase Chain Reaction, Vestibular Nuclei
Abstract

<p>The distribution of herpes simplex virus type 1 (HSV-1) in human geniculate, vestibular ganglia, and vestibular nuclei was determined in 10 human temporal bones and brainstems of five individuals by PCR. HSV-1 was found in 3 of 10 of each ganglia and vestibular nuclei. The various patterns of HSV-1 infection of vestibular structures are compatible with virus migration from the vestibular ganglia to the vestibular nuclei and from the ipsilateral to the contralateral vestibular nucleus via commissural fibers.</p>

Alternate JournalNeurology
Citation KeyCK72
PubMed ID10994016