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Viruses and vestibular neuritis: review of human and animal studies.

TitleViruses and vestibular neuritis: review of human and animal studies.
Publication TypeJournal Article
Year of Publication1993
AuthorsDavis LE
JournalActa Otolaryngol Suppl
Volume503
Pagination70-3
Date Published1993
ISSN0365-5237
KeywordsAnimals, Antigens, Viral, Fluorescent Antibody Technique, Humans, Meniere Disease, Neuritis, Vestibular Nerve, Vestibulocochlear Nerve Diseases, Virus Diseases
Abstract

<p>There is increasing evidence in man and animals that several human viruses can damage the vestibular labyrinth. Clinical and serologic studies of patients with vestibular neuritis suggest that the viruses may play a role in the pathogenesis of this disease. Temporal bone studies of patients dying after vestibular neuritis have found maximal damage in the distal branches of the vestibular nerve. These changes are felt to be consistent with a viral etiology. No satisfactory animal viral model of vestibular neuritis currently exists. However, animal studies have demonstrated that several human viruses including rubeola, herpes simplex, reovirus, mouse and guinea pig cytomegalovirus, and neurotropic strains of influenza A and mumps virus, can infect the vestibular nerve and the vestibular membranous labyrinth.</p>

Alternate JournalActa Otolaryngol Suppl
Citation KeyCK79
PubMed ID8470506