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Histopathology of idiopathic chronic recurrent vertigo.

TitleHistopathology of idiopathic chronic recurrent vertigo.
Publication TypeJournal Article
Year of Publication1996
AuthorsIshiyama A, Ishiyama GP, Lopez I, Eversole LR, Honrubia V, Baloh RW
Date Published1996 Nov
KeywordsCochlear Nerve, Female, Humans, Male, Middle Aged, Nerve Endings, Neuritis, Recurrence, Vertigo, Vestibular Nerve, Vestibulocochlear Nerve Diseases

<p>Vestibular neuritis is a degenerative neuropathy of the peripheral vestibular system. The etiology of this condition is uncertain, although it is generally believed to be viral. A small percentage of patients with vestibular neuritis have chronic recurrent episodes of vertigo. Detailed cytologic descriptions of acute or chronic vestibular neuritis are lacking, and no previous studies have reported evidence of chronic inflammation in human temporal bone specimens. The authors of this study examined temporal bone specimens from three patients with a history of chronic recurrent vertigo of unknown cause. Varying degrees of inflammation and destruction were seen in the vestibular system, and mild involvement of the cochlear system was noted. These findings are consistent with postinfectious inflammatory changes of the cochlear-vestibular system analogous to a postinfectious syndrome involving the central nervous system.</p>

Alternate JournalLaryngoscope
Citation KeyCK92
PubMed ID8914898
Grant ListAG 09693 / AG / NIA NIH HHS / United States
DC 01404 / DC / NIDCD NIH HHS / United States